Recombinant ATG5 anticorps (AA 1-119)
Aperçu rapide pour Recombinant ATG5 anticorps (AA 1-119) (ABIN7127196)
Antigène
Voir toutes ATG5 AnticorpsType d'anticorp
Reactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 1-119
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Specificité
- The protein encoded by this gene, in combination with autophagy protein 12, functions as an E1-like activating enzyme in a ubiquitin-like conjugating system. The encoded protein is involved in several cellular processes, including autophagic vesicle formation, mitochondrial quality control after oxidative damage, negative regulation of the innate antiviral immune response, lymphocyte development and proliferation, MHC II antigen presentation, adipocyte differentiation, and apoptosis. The ATG5 protein is essential for autophagy, a process that is usually beneficial for cells to self-degrade their own components when they are no longer useful.
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Réactivité croisée (Details)
- Human.
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Purification
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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Immunogène
- Recombinant fragment of human ATG5 protein (around aa 1-119) (exact sequence is proprietary)
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Isotype
- IgG
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Indications d'application
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Known_Application: ELISA (For coating, order antibody without BSA),Optimal dilution for a specific application should be determined.
Positive_Control: K562, U-87, A431, THP-1, PANC-1, Raji or HeLa cells. Ovary, Endometrium, Colon or Duodenum.
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Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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Agent conservateur
- Azide free
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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Date de péremption
- 24 months
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- ATG5 (ATG5 Autophagy Related 5 (ATG5))
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Autre désignation
- ATG5
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Sujet
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APG5 autophagy 5 like (APG5L), Apoptosis-specific protein (ASP), ATG5, Autophagy related 5, hAPG5,ATG5 (Autophagy Marker)
Cellular localisation: Cytoplasmic -
Poids moléculaire
- 32kDa
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ID gène
- 9474, 486063
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UniProt
- Q9H1Y0
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Pathways
- Activation of Innate immune Response, Production of Molecular Mediator of Immune Response, Autophagy
Antigène
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